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Flights from Orlando to Panama City

What to know about flights from Orlando to Panama City?

The distance between Orlando and Panama City is approximately 456.58 km. Based on Trip.com's data, travel demand peaks in January.

Cheapest one-way
$190
Delta Air Lines Delta Air Lines ORL-ECP 3h 46m · 1 stop Wed, Sep 16
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Cheapest round-trip
$375
Delta Air Lines Delta Air Lines ORL-ECP 6h 38m · 2 stops Thu, Oct 15 - Tue, Oct 20
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Recommended airlines
Delta Air Lines Delta Air Lines Cheapest · From $190 Delta Air Lines Delta Air Lines Most booked
When to travel
October
Cheapest
January
Peak season for travel
Route details
456.58 km
Flight distance

Explore the cheapest one-way and round-trip flights from Orlando to Panama City over the next 90 days, with one-way fares from $190 and round-trip from $375. Based on Trip.com's latest 7-day flight data.

      • MCO 5:40 PM
        6h 38m
        1 stop
        ECP 11:18 PM
        Orlando - Panama City | Thu, Oct 15 | Delta Air Lines
        ECP 7:12 AM
        4h 47m
        1 stop
        MCO 12:59 PM
        Panama City - Orlando | Tue, Oct 20 | Delta Air Lines
        $375 $1,060
        65% off
        65% off
        $1,060 $375
      • MCO 9:05 AM
        4h 34m
        1 stop
        ECP 12:39 PM
        Orlando - Panama City | Sat, Sep 12 | Delta Air Lines
        ECP 4:35 PM
        7h 43m
        1 stop
        MCO 1:18 AM
        Panama City - Orlando | Tue, Sep 15 | Delta Air Lines
        $380 $1,060
        64% off
        64% off
        $1,060 $380
      • MCO 5:30 AM
        3h 48m
        1 stop
        ECP 8:18 AM
        Orlando - Panama City | Sun, Sep 20 | Delta Air Lines
        ECP 6:19 PM
        5h 59m
        1 stop
        MCO 1:18 AM
        Panama City - Orlando | Tue, Sep 22 | Delta Air Lines
        $405 $1,060
        62% off
        62% off
        $1,060 $405
      • MCO 7:45 PM
        4h 33m
        1 stop
        ECP 11:18 PM
        Orlando - Panama City | Thu, Oct 22 | Delta Air Lines
        ECP 6:00 AM
        6h 30m
        1 stop
        MCO 1:30 PM
        Panama City - Orlando | Mon, Oct 26 | Delta Air Lines
        $462
        56% off
        $1,060 $462
      • MCO 6:16 AM
        15h 51m
        1 stop
        ECP 9:07 PM
        Orlando - Panama City | Sun, Sep 20 | American Airlines
        ECP 4:27 PM
        25h 44m
        1 stop
        MCO 7:11 PM
        Panama City - Orlando | Tue, Sep 22 | American Airlines
        $676
        36% off
        $1,060 $676
      • MCO 12:50 PM
        6h 23m
        1 stop
        ECP 6:13 PM
        Orlando - Panama City | Thu, Oct 15 | American Airlines
        ECP 7:12 AM
        3h 48m
        1 stop
        MCO 12:00 PM
        Panama City - Orlando | Tue, Oct 20 | Delta Air Lines
        $837
        21% off
        $1,060 $837
      • ORL 1:00 PM
        17h 25m
        1 stop
        ECP 2:00 PM
        Orlando - Panama City | Fri, Sep 11 | Normal Airline
        ECP 3:00 PM
        6h
        Nonstop
        ORL 4:00 PM
        Panama City - Orlando | Sun, Sep 13 | Normal Airline
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      • MCO 5:30 AM
        3h 46m
        1 stop
        ECP 8:16 AM
        Orlando - Panama City | Wed, Sep 16 | Delta Air Lines
        $190 $332
        43% off
        43% off
        $332 $190
      • MCO 6:40 PM
        5h 45m
        1 stop
        ECP 11:25 PM
        Orlando - Panama City | Sun, Sep 13 | Delta Air Lines
        $201 $332
        39% off
        39% off
        $332 $201
      • MCO 8:10 AM
        7h 47m
        1 stop
        ECP 2:57 PM
        Orlando - Panama City | Wed, Sep 16 | Frontier Airlines
        $221 $332
        33% off
        33% off
        $332 $221
      • MCO 10:15 AM
        11h 20m
        1 stop
        ECP 8:35 PM
        Orlando - Panama City | Wed, Sep 16 | Hahn Air
        $229
        31% off
        $332 $229
      • MCO 5:30 AM
        3h 44m
        1 stop
        ECP 8:14 AM
        Orlando - Panama City | Sun, Oct 11 | Delta Air Lines
        $230
        31% off
        $332 $230
      • MCO 5:30 AM
        6h 4m
        1 stop
        ECP 10:34 AM
        Orlando - Panama City | Fri, Oct 2 | Delta Air Lines
        $252
        24% off
        $332 $252
      • MCO 7:00 AM
        6h 39m
        1 stop
        ECP 12:39 PM
        Orlando - Panama City | Sat, Oct 3 | Delta Air Lines
        $252
        24% off
        $332 $252
      • MCO 7:50 PM
        4h 35m
        1 stop
        ECP 11:25 PM
        Orlando - Panama City | Thu, Oct 1 | Delta Air Lines
        $254
        23% off
        $332 $254
      • MCO 6:16 AM
        9h 6m
        1 stop
        ECP 2:22 PM
        Orlando - Panama City | Sat, Oct 3 | American Airlines
        $262
        21% off
        $332 $262
      • ORL 1:00 PM
        17h 25m
        1 stop
        ECP 2:00 PM
        Orlando - Panama City | Fri, Sep 11 | Normal Airline
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Which airlines are the most popular for Orlando to Panama City flights?

You can choose from 1 airlines that fly from Orlando to Panama City, including Delta Air Lines, Delta Air Lines has lowest fares on this route.
Delta Air Lines logo Delta Air Lines
Airlines are determined based on actual purchased flight tickets from Orlando to Panama City according to previous 12 months data from Trip.com.

Frequently Asked Questions

  • What are the cheapest flights from Orlando to Panama City (ORL-ECP)?

    Based on Trip.com data, Delta Air Lines offers one-way fares as low as $190 on Cheapest nonstop routes (e.g. MCO to ECP on Wed, Sep 16), while Delta Air Lines offers Cheapest nonstop round-trips from $375 departing on Thu, Oct 15 and returning on Tue, Oct 20.
  • At the moment, several airlines serve connecting flights from Orlando to Panama City, including: Delta Air Lines Selected airlines are based on historical data collected from flight bookings made by users on Trip.com within the last 90 days.
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Orlando to Panama City is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Orlando to Panama City, you can use various tools on Trip.com:
    · Be flexible with your travel dates to get the cheapest flight deal. Now the cheapest flight deal is on Wed, Sep 16, with one-way flights priced at just $190.
    · Compare airlines strategically. Budget carriers often provide the lowest base fares, while we found the most affordable airline currently operating on this route is Delta Air Lines.
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Panama City travel is around January.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Orlando to Panama City is October, when demand for travel is lower.
  • After crunching the numbers on our September flight calendar, it's currently cheapest to fly from Orlando to Panama City on September 10, 2026 with Delta Air Lines, with prices starting at $305.
  • You can arrive at any of the following airports in Panama City: Northwest Florida Beaches International Airport (ECP). Flights from Orlando International Airport to Northwest Florida Beaches International Airport (MCO-ECP) are by far the most popular option for this route.
  • The time difference between Panama City and Orlando is 1h.
  • Tickets can only be changed or canceled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.
  • Based on Trip.com data for flights departing in the next 30 days, the average one-way fare from Orlando to Panama City is $345. Fares vary by travel date, airline and availability.
  • Enter Orlando and Panama City, choose your travel dates and passengers, then compare flights by price, duration and baggage. Select a fare, review the change and cancellation rules, enter traveler details and complete payment to receive your confirmation.

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Note: Prices shown on this page are estimated lowest price and include all taxes and fees found in the last 24 hours.

Book with no extra fees

Prices displayed in this page are all-inclusive prices (incl. taxes, fuel surcharge, civil aviation development fund, etc) with all fees confirmed before payment. Fees for luggage, meals, WLAN, or other additional services are also included as shown in the flight cards.

Real-time pricing updates

Prices, availability, and travel information on this page were updated within last 24 hours—even in real-time. The more popular the route, the more precise the data.

Change & Cancellation Policy

Trip.com displays flight cancellation and change policies for each flight ticket during the booking process, including fees and applicable conditions. Please check the following scenarios:
Voluntary cancellation/change:
To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy.
Cancellation/change due to a flight schedule change:
If the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.