Find cheap flights from Chicago to Santiago starting at $344.
Book one-way or return flights from Chicago to Santiago from as little as $344. Choose from the popular airlines below and book your flight today!
- One way
- Round-trip
- MDW15:4514h 15m1 stopSCL07:00Sat, May 4|Chicago - Santiago|LATAM Airlines$344$45625% OFF25% OFF$456$344
- ORD15:1027h 10m1 stopSCL19:20Wed, May 8|Chicago - Santiago|Copa Airlines$351$45623% OFF23% OFF$456$351
- ORD11:1418h 21m1 stopSCL06:35Wed, May 8|Chicago - Santiago|Spirit Airlines$358$45622% OFF22% OFF$456$358
- ORD18:5434h 51m1 stopSCL06:45Tue, Jun 11|Chicago - Santiago|American Airlines$387$387
- ORD21:1532h 35m1 stopSCL06:50Tue, May 21|Chicago - Santiago|Spirit Airlines$387$387
- ORD15:1012h 59m1 stopSCL05:09Sun, Jun 16|Chicago - Santiago|Copa Airlines$403$403
- MDW14:3615h 9m1 stopSCL06:45Thu, Jun 13|Chicago - Santiago|Frontier Airlines$404$404
- ORD15:1012h 59m1 stopSCL05:09Thu, Jul 11|Chicago - Santiago|Copa Airlines$408$408
- ORD07:5614h 1m1 stopSCL22:57Thu, May 16|Chicago - Santiago|Copa Airlines$419$419
- ORD12:1017h 25m1 stopSCL06:35Wed, May 8|Chicago - Santiago|American Airlines$420$420
- CHI13:003h 5mDirectSCL14:00Fri, May 10|Chicago - Santiago|LATAM AirlinesFind More FlightsFind More Flights
Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
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Find more flights and airlines
Discover different routes, airlines, and transfers and find the best alternative flights for your journey from Chicago to Santiago.
- CheapestMDW19:1741h 8m2 transferSCL13:25Midway International Airport - Arturo Merino Benitez AirportWed, May 15Frontier Airlines$209
- ORD07:1219h 58m2 transferSCL04:10O'Hare International Airport - Arturo Merino Benitez AirportSat, May 11Spirit Airlines$291
- ORD07:1219h 58m2 transferSCL04:10O'Hare International Airport - Arturo Merino Benitez AirportSat, May 11Spirit Airlines$291Find More Flights
Frequently Asked Questions
How to find a cheap flight from Chicago to Santiago
Cheapest nonstop flight price | $344 |
---|---|
Off-season for travel | December |
Peak season for travel | July |
Flight distance | 8,544.66km |
Popular airline | American Airlines |
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