Cheap flight from Chicago to Santiago from $639
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Flights from Chicago to Santiago
Find cheap airlines flights from Chicago to Santiago
Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.
Cheap flight deals from Chicago to Santiago
We've found these cheap flights for you. You can book one-way or round-trip flight tickets.
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One way
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ORD 1:31 PM16h 14m1 stopsSCL 6:45 AMChicago - Santiago | Mon, Jun 23 | LATAM Airlines
SCL 10:55 PM19h 51m1 stopsORD 5:46 PMSantiago - Chicago | Mon, Jun 30 | LATAM Airlines$639 $88828% OFF28% OFF$888 $639 -
MDW 10:26 AM19h 34m1 stopsSCL 7:00 AMChicago - Santiago | Wed, Jun 25 | LATAM Airlines
SCL 8:40 PM14h 1m1 stopsMDW 9:41 AMSantiago - Chicago | Wed, Jul 2 | LATAM Airlines$639 $88828% OFF28% OFF$888 $639
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ORD 9:49 AM20h 11m1 stopsSCL 7:00 AMChicago - Santiago | Thu, Jun 26 | LATAM Airlines
SCL 8:40 PM14h 1m1 stopsMDW 9:41 AMSantiago - Chicago | Thu, Jul 3 | LATAM Airlines$643 $88828% OFF28% OFF$888 $643
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MDW 12:44 PM17h 16m1 stopsSCL 7:00 AMChicago - Santiago | Thu, Jun 26 | Delta Air Lines
SCL 8:40 PM14h 21m1 stopsORD 10:01 AMSantiago - Chicago | Thu, Jul 3 | Delta Air Lines$66226% OFF$888 $662 -
ORD 5:59 PM12h 1m1 stopsSCL 7:00 AMChicago - Santiago | Mon, Jun 23 | Delta Air Lines
SCL 8:40 PM21h 9m1 stopsORD 4:49 PMSantiago - Chicago | Mon, Jun 30 | Delta Air Lines$66425% OFF$888 $664
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MDW 6:00 AM24h1 stopsSCL 7:00 AMChicago - Santiago | Mon, Jun 30 | Delta Air Lines
SCL 8:40 PM23h 9m1 stopsORD 6:49 PMSantiago - Chicago | Mon, Jul 7 | Delta Air Lines$66425% OFF$888 $664
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MDW 12:44 PM17h 16m1 stopsSCL 7:00 AMChicago - Santiago | Wed, Jun 25 | Delta Air Lines
SCL 8:40 PM14h 1m1 stopsMDW 9:41 AMSantiago - Chicago | Wed, Jul 2 | Delta Air Lines$67025% OFF$888 $670
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ORD 2:35 PM21h 50m1 stopsSCL 1:25 PMChicago - Santiago | Mon, Aug 18 | avianca
SCL 2:30 PM23h 45m1 stopsORD 1:15 PMSantiago - Chicago | Sat, Aug 23 | avianca$67125% OFF$888 $671 -
ORD 2:35 PM21h 50m1 stopsSCL 1:25 PMChicago - Santiago | Mon, Jul 28 | avianca
SCL 2:30 PM23h 45m1 stopsORD 1:15 PMSantiago - Chicago | Sun, Aug 3 | avianca$67224% OFF$888 $672
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ORD 2:35 PM21h 50m1 stopsSCL 1:25 PMChicago - Santiago | Thu, Aug 14 | avianca
SCL 2:30 PM23h 45m1 stopsORD 1:15 PMSantiago - Chicago | Mon, Aug 18 | avianca$67524% OFF$888 $675
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CHI 1:00 PM17h 25m1 stopsSCL Invalid DateChicago - Santiago | Sun, Jun 22 | Normal Airline
SCL 3:00 PM6hNonstopCHI 4:00 PMSantiago - Chicago | Tue, Jun 24 | Normal AirlineFind More FlightsFind More Flights
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ORD 2:35 PM21h 50m1 stopsSCL 1:25 PMChicago - Santiago | Sun, Jun 29 | avianca$302 $46335% OFF35% OFF$463 $302
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ORD 2:35 PM12h 40m1 stopsSCL 4:15 AMChicago - Santiago | Fri, Jun 20 | avianca$318 $46331% OFF31% OFF$463 $318
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ORD 2:35 PM12h 40m1 stopsSCL 4:15 AMChicago - Santiago | Fri, Aug 15 | avianca$322 $46330% OFF30% OFF$463 $322
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ORD 2:35 PM21h 50m1 stopsSCL 1:25 PMChicago - Santiago | Wed, Aug 13 | avianca$32330% OFF$463 $323
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ORD 2:35 PM21h 50m1 stopsSCL 1:25 PMChicago - Santiago | Mon, Aug 18 | avianca$32330% OFF$463 $323
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ORD 2:35 PM12h 40m1 stopsSCL 4:15 AMChicago - Santiago | Tue, Aug 12 | avianca$32330% OFF$463 $323
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ORD 2:35 PM21h 50m1 stopsSCL 1:25 PMChicago - Santiago | Thu, Aug 14 | avianca$32330% OFF$463 $323
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ORD 2:35 PM21h 50m1 stopsSCL 1:25 PMChicago - Santiago | Sun, Aug 10 | avianca$32330% OFF$463 $323
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ORD 2:35 PM12h 40m1 stopsSCL 4:15 AMChicago - Santiago | Mon, Aug 4 | avianca$35124% OFF$463 $351
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ORD 2:35 PM21h 50m1 stopsSCL 1:25 PMChicago - Santiago | Sat, Aug 9 | avianca$35224% OFF$463 $352
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CHI 1:00 PM17h 25m1 stopsSCL Invalid DateChicago - Santiago | Sun, Jun 22 | Normal AirlineFind More FlightsFind More Flights
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
Flight Info | Chicago to Santiago
| Cheapest one-way flight price | $301 |
|---|---|
| Off-season for travel | April |
| Peak season for travel | June |
| Flight distance | 8,544.66 km |
| Popular airline | Aeromexico |
When is the cheapest time to fly from Chicago to Santiago?
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Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Frequently Asked Questions
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When are flight tickets from Chicago (CHI) to Santiago (SCL) the cheapest?
Airlines adjust prices for flights from Chicago to Santiago based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays. -
How much do flights from Chicago (CHI) to Santiago (SCL) cost?
According to Trip.com's data, the lowest price is around $904.
How to find a cheap flight from Chicago to Santiago
Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Chicago to Santiago. Book your flights at the right time and save more.
Be flexible with your travel dates to get the cheapest Chicago to Santiago ticket.
Tap "Date" in the flight search bar to browse the calendar and find airfare from Chicago to Santiago for the next six months in 2025. If you're looking to fly within the next three months, the lowest fare is $302 for a one-way ticket on Sun, Jun 29.
Compare cheap Chicago to Santiago flight deals from hundreds of airlines.
Our powerful search system compares prices from over 500 airlines. So you can find the cheapest flights from Chicago to Santiago. The most affordable airline currently operating on this route is avianca.
Set up a Price Alert to track fare drops.
Set up a Price Alert for your Chicago to Santiago route to track ticket prices effortlessly—no need to check manually every day.
Don't miss out on cheap Chicago to Santiago flight deals and promo codes.
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Book early or wait unitl the last minute to fine the best fares.
It's always better to book early! Airlines typically release their lowest fares about a year before departure, so check as soon as flights become available. If you miss that window, you may still find great deals closer to your travel date.
Search for flights on the go.
For the best booking experience on the go, download Trip.com and search for cheap flights from Chicago to Santiago to access exclusive deals just for you.
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