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Cheap flight deals from Syracuse to Knoxville Starting at $151

Whether you’re going for a one-way or round-trip to Knoxville, we’ve got you covered! Check out these different flight options from Syracuse below.

  • One way
  • Round-trip
      • SYR06:00 am
        14h 32m
        1 stop
        TYS08:32 pm
        Sun, Jan 19|Syracuse - Knoxville|Jetblue Airways
        $151$278
        46% OFF
        46% OFF
        $278$151

        Choose Jetblue Airways flights from Syracuse to Knoxville. The one-way connecting flight with Jetblue Airways departs from Syracuse Hancock International Airport on Sun, Jan 19, arriving at Mcghee Tyson Airport. One-way Prices start from $151 including taxes and charges.

      • SYR06:10 am
        5h 13m
        1 stop
        TYS11:23 am
        Mon, Jan 20|Syracuse - Knoxville|Delta Air Lines
        $192$278
        31% OFF
        31% OFF
        $278$192

        Choose Delta Air Lines flights from Syracuse to Knoxville. The one-way connecting flight with Delta Air Lines departs from Syracuse Hancock International Airport on Mon, Jan 20, arriving at Mcghee Tyson Airport. One-way Prices start from $192 including taxes and charges.

      • SYR06:02 am
        4h 42m
        1 stop
        TYS10:44 am
        Mon, Jan 20|Syracuse - Knoxville|United Airlines
        $226$278
        19% OFF
        19% OFF
        $278$226

        Choose United Airlines flights from Syracuse to Knoxville. The one-way connecting flight with United Airlines departs from Syracuse Hancock International Airport on Mon, Jan 20, arriving at Mcghee Tyson Airport. One-way Prices start from $226 including taxes and charges.

      • SYR06:02 am
        4h 42m
        1 stop
        TYS10:44 am
        Thu, Jan 30|Syracuse - Knoxville|United Airlines
        $231
        $231

        Choose United Airlines flights from Syracuse to Knoxville. The one-way connecting flight with United Airlines departs from Syracuse Hancock International Airport on Thu, Jan 30, arriving at Mcghee Tyson Airport. One-way Prices start from $231 including taxes and charges.

      • SYR08:20 am
        12h 13m
        1 stop
        TYS08:33 pm
        Sun, Jan 19|Syracuse - Knoxville|Delta Air Lines
        $232
        $232

        Choose Delta Air Lines flights from Syracuse to Knoxville. The one-way connecting flight with Delta Air Lines departs from Syracuse Hancock International Airport on Sun, Jan 19, arriving at Mcghee Tyson Airport. One-way Prices start from $232 including taxes and charges.

      • SYR06:02 am
        4h 42m
        1 stop
        TYS10:44 am
        Sat, Feb 1|Syracuse - Knoxville|United Airlines
        $232
        $232

        Choose United Airlines flights from Syracuse to Knoxville. The one-way connecting flight with United Airlines departs from Syracuse Hancock International Airport on Sat, Feb 1, arriving at Mcghee Tyson Airport. One-way Prices start from $232 including taxes and charges.

      • SYR10:23 am
        4h 20m
        1 stop
        TYS02:43 pm
        Mon, Feb 10|Syracuse - Knoxville|United Airlines
        $233
        $233

        Choose United Airlines flights from Syracuse to Knoxville. The one-way connecting flight with United Airlines departs from Syracuse Hancock International Airport on Mon, Feb 10, arriving at Mcghee Tyson Airport. One-way Prices start from $233 including taxes and charges.

      • SYR10:23 am
        4h 20m
        1 stop
        TYS02:43 pm
        Wed, Feb 12|Syracuse - Knoxville|United Airlines
        $233
        $233

        Choose United Airlines flights from Syracuse to Knoxville. The one-way connecting flight with United Airlines departs from Syracuse Hancock International Airport on Wed, Feb 12, arriving at Mcghee Tyson Airport. One-way Prices start from $233 including taxes and charges.

      • SYR10:23 am
        4h 20m
        1 stop
        TYS02:43 pm
        Sun, Jan 19|Syracuse - Knoxville|United Airlines
        $233
        $233

        Choose United Airlines flights from Syracuse to Knoxville. The one-way connecting flight with United Airlines departs from Syracuse Hancock International Airport on Sun, Jan 19, arriving at Mcghee Tyson Airport. One-way Prices start from $233 including taxes and charges.

      • SYR06:02 am
        4h 42m
        1 stop
        TYS10:44 am
        Thu, Jan 23|Syracuse - Knoxville|United Airlines
        $236
        $236

        Choose United Airlines flights from Syracuse to Knoxville. The one-way connecting flight with United Airlines departs from Syracuse Hancock International Airport on Thu, Jan 23, arriving at Mcghee Tyson Airport. One-way Prices start from $236 including taxes and charges.

      • SYR01:00 pm
        3h 5m
        Nonstop
        TYS02:00 pm
        Sun, Jan 12|Syracuse - Knoxville|Jetblue Airways
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

When is the cheapest time to fly from Syracuse to Knoxville?

Price trend charts are a great way of tracking how much your flights cost in the lead up to departure and can help you choose when to book your tickets. See how prices to Knoxville from Syracuse have changed and are set to move below.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Find cheap airlines flights from Syracuse to Knoxville

Compare prices from various providers below to understand which option best suits your travel needs, before enjoying a comfortable journey with a trusted airline from Syracuse to Knoxville.

Jetblue Airways
From $151
Delta Air Lines
From $192
United Airlines
From $226
American Airlines
From $243

Find more flights and airlines

Alternative Cheap Routes from Syracuse to Knoxville

Searching for potential routes that might be cheaper and faster? There are a few alternative ways to get to Knoxville from Syracuse which could help you save money and time.

  • Cheapest
    Jetblue Airways
    SYR
    06:00 am
    14h 32m
    1 transfer
    TYS
    08:32 pm
    Syracuse Hancock International Airport - Mcghee Tyson Airport
    Sun, Jan 19Jetblue Airways
    $151
  • Jetblue Airways
    SYR
    06:00 am
    14h 32m
    1 transfer
    TYS
    08:32 pm
    Syracuse Hancock International Airport - Mcghee Tyson Airport
    Sun, Jan 19Jetblue Airways
    $151
    Find More Flights

Frequently Asked Questions

  • When are flight tickets from Syracuse (SYR) to Knoxville (TYS) the cheapest?

    Airlines adjust prices for flights from Syracuse to Knoxville based on the departure date and time of your selection. By analyzing data from all airlines, we've discovered that on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Syracuse (SYR) to Knoxville (TYS) cost?

    According to Trip.com's data, the lowest price is around $457.

How to find a cheap flight from Syracuse to Knoxville

Understanding the common pitfalls when booking your flight tickets can help you save massively when it comes time to fly. We’ve listed our six essential steps to keep in mind when you’re booking flight tickets to help you find the best price.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Info | Syracuse to Knoxville

Cheapest nonstop flight price$151
Off-season for travelJanuary
Peak season for travelOctober
Flight distance1,056.06 km
Popular airlineAmerican Airlines

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